We advise against this as it is possible that legitimate email will be deleted and the sender will never know that you didn't receive it. We recommend filtering the email in your email client and placing it in a separate folder so that you can check through it in your own time.
Instructions on how to set-up filtering can be found at the two links below:
If you're happy that email marked as {Spam?}, and/or more suitably {Definitely Spam?} you can then configure MailScanner to delete that email.
Another alternative is to have all email marked as {Spam?}, and/or more suitably {Definitely Spam?} delivered to a specific email address. For example, spam@mydomain.com.